HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16429126, 15766533, 31399574
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000492 - box C/D snoRNP assembly GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity GO:0050821 - protein stabilization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 463
+	Hs
		438632 HS90B_HUMAN (5-709): 0: 1026: 62.13		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Sc
		544350 HSC82_YEAST (1-709): 0: 973: 94.64		RUVB1_YEAST (1-463): 0: 682: 100.00
+	Hs
		432374 HS90A_HUMAN (4-709): 0: 1015: 60.83		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Ca
		804508 HSP90_CANAL (4-709): 0: 959: 81.75		RUVB1_CANAL (1-463): 0: 661: 78.45
+	Sc
		367127 HSP82_YEAST (1-709): 0: 984: 100.00		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Sc
		544639 HSC82_YEAST (1-709): 0: 973: 94.64		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Ca
		804543 HSP90_CANAL (4-709): 0: 959: 81.75		RUVB2_CANAL (21-461): 0: 618: 41.99