HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: K2C79 (Q5XKE5)
Keratin, type II cytoskeletal 79 (Cytokeratin-79) (CK-79) (Keratin-6-like) (Keratin-6L) (Keratin-79) (K79) (Type-II keratin Kb38)
Gene: KRT79

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 535
+	Hs
		368816 ESR1_HUMAN (1-595): 0: 599: 100.00		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		369912 ESR1_HUMAN (1-595): 0: 599: 100.00		K2C1B_HUMAN (36-476): 1.35e-81: 267: 59.48
+	Hs
		368958 ESR1_HUMAN (1-595): 0: 599: 100.00		K2C4_HUMAN (5-475): 4.17e-70: 235: 62.61
+	Hs
		370133 ESR1_HUMAN (1-595): 0: 599: 100.00		KRT35_HUMAN (53-500): 2.1e-64: 218: 23.11
+	Hs
		611385 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		K22E_HUMAN (114-460): 1.25e-156: 462: 70.03
+	Hs
		318855 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		K2C75_HUMAN (3-535): 2.44e-90: 289: 57.27
+	Hs
		213976 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		KRT86_HUMAN (5-523): 1.04e-90: 288: 42.15
+	Hs
		943688 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		KRT85_HUMAN (2-510): 1.4e-88: 283: 43.14
+	Hs
		1062061 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		K2C72_HUMAN (23-522): 5.54e-77: 253: 55.36
+	Hs
		580147 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		K2C4_HUMAN (5-475): 4.17e-70: 235: 62.61
+	Hs
		408982 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		487082 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		K2C3_HUMAN (114-462): 3.51e-65: 225: 73.93