HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: PLXA1 (P70206)
Plexin-A1 (Plex 1) (Plexin-1)
Gene: Plxna1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Mm			1 1894
+	Hs
		1345087 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		PLXA1_HUMAN (1-1894): 0: 2608: 96.04
+	Hs
		1329636 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		PLXA1_HUMAN (1-1894): 0: 2608: 96.04
+	Hs
		177747 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		PLXA2_HUMAN (36-1894): 0: 2420: 63.46
+	Hs
		253503 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		PLXA2_HUMAN (36-1894): 0: 2420: 63.46
+	Hs
		177847 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		PLXA3_HUMAN (37-1894): 0: 2350: 66.77
+	Hs
		850504 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		PLXA3_HUMAN (37-1894): 0: 2350: 66.77
+	Hs
		165175 TMPS3_HUMAN (10-257): 7.5e-103: 308: 29.57		PLXB2_HUMAN (36-1891): 0: 1965: 32.52
+	Mm
		71302 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		PLXB2_MOUSE (36-1891): 0: 1947: 32.10
+	Hs
		165219 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		PLXB2_HUMAN (36-1891): 0: 1965: 32.52
+	Hs
		165123 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		PLXB2_HUMAN (36-1891): 0: 1965: 32.52
+	Hs
		165259 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		PLXB2_HUMAN (36-1891): 0: 1965: 32.52
+	Mm
		139664 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SEM3A_MOUSE (44-541): 1.29e-128: 424: 15.19
+	Mm
		371942 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SEM4B_MOUSE (27-617): 7.62e-128: 424: 18.21
+	Mm
		292031 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SEM3F_MOUSE (12-547): 6.35e-125: 414: 16.69
+	Hs
		420743 KLK1_HUMAN (5-257): 1.35e-96: 285: 33.21		SEM3B_HUMAN (9-545): 1.66e-133: 438: 18.00
+	Hs
		1271968 KLK6_HUMAN (1-255): 6.18e-98: 288: 32.69		SEM4G_HUMAN (9-539): 2.18e-121: 406: 18.75
+	Hs
		441530 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		MET_HUMAN (812-1290): 3.95e-101: 359: 23.36
+	Hs
		177794 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		MET_HUMAN (812-1290): 3.95e-101: 359: 23.36
+	Hs
		441573 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		MET_HUMAN (812-1290): 3.95e-101: 359: 23.36
+	Hs
		981921 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		RON_HUMAN (813-1210): 1.04e-82: 302: 25.48