HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: LASP1 (Q14847)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 261
+	Hs
		373060 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PACN1_HUMAN (7-261): 5.39e-26: 107: 19.48
+	Hs
		104676 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		F6U236_HUMAN (7-261): 6.73e-26: 106: 19.48
+	Hs
		373441 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		DBNL_HUMAN (59-261): 1.64e-25: 106: 23.65
+	Hs
		371901 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MYO1E_HUMAN (36-261): 9.05e-25: 104: 15.04
+	Hs
		372014 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SRC8_HUMAN (38-260): 1.53e-23: 101: 17.62
+	Hs
		372969 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SH3G1_HUMAN (48-261): 4.4e-24: 101: 18.81
+	Hs
		371090 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PLCG2_HUMAN (17-261): 3.52e-22: 97.6: 13.88
+	Hs
		371539 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		CRIP2_HUMAN (1-54): 1.17e-17: 80.7: 42.59
+	Hs
		373050 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SRBS1_HUMAN (149-259): 7.57e-13: 69.9: 31.30
+	Hs
		406807 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		BAIP2_HUMAN (19-261): 1.08e-24: 104: 15.75
+	Hs
		405909 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		CRIP1_HUMAN (3-54): 2.23e-22: 89.5: 46.15
+	Hs
		405933 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		CRIP2_HUMAN (1-54): 1.17e-17: 80.7: 42.59