Interactor 1: MMP1 (P03956)
Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]
Gene: MMP1
Interactor 2: TIMP4 (Q99727)
Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)
Gene: TIMP4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 1.00 | 0.735 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12475252 |
| Identification Methods | surface plasmon resonance, enzymatic study |
| Interaction Type | direct interaction, enzymatic reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hemopexin~TIMP, Peptidase_M10~TIMP |
| Common GO terms | GO:0005615 - extracellular space GO:0031012 - extracellular matrix |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
