Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1
Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.990 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25852190, 12620389, 31980649, 10620507, 10848612, 8702721, 7644510, 35271311, 32707033, 16041367, 12360521, 33961781, 36931259, 11697890, 16093354, 24255178, 7935795, unassigned2173, 37045861, 7882972 and 3 others
more... |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, biochemical |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 14-3-3~C1_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0019899 - enzyme binding |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
