HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	31980649, unassigned2173, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 535
+	Hs
		374759 RAF1_HUMAN (1-648): 0: 652: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		373876 RAF1_HUMAN (1-648): 0: 652: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		373647 RAF1_HUMAN (1-648): 0: 652: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		373868 RAF1_HUMAN (1-648): 0: 652: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		542913 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		488790 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		488674 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		488618 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		488566 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		433319 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		412325 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		412130 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		433290 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		412086 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		433248 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		411996 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		412084 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Dm
		507695 KRAF1_DROME (45-647): 6.35e-165: 491: 44.98		TCPA_DROME (1-528): 7.49e-82: 267: 34.55