HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: DEP1B (Q8WUY9)
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)
Gene: DEPDC1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 529
+	Hs
		375772 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		1145037 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		374807 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		976450 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		956423 RAB2A_HUMAN (4-185): 5.47e-74: 223: 31.52		DEP1B_HUMAN (1-529): 3.15e-178: 513: 100.00
+	Hs
		49953 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		RHG10_HUMAN (58-528): 1.85e-73: 250: 13.06
+	Hs
		67597 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		RHG32_HUMAN (147-497): 3.7e-60: 217: 14.58
+	Hs
		67671 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		RHG32_HUMAN (147-497): 3.7e-60: 217: 14.58
+	Hs
		375700 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		RHG12_HUMAN (78-393): 5.87e-56: 203: 15.74
+	Hs
		375564 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		RHG31_HUMAN (243-402): 1.88e-34: 140: 20.71
+	Hs
		976406 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		RHG18_HUMAN (194-416): 3.99e-38: 150: 16.39