HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: TANC1 (Q9C0D5)
Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)
Gene: TANC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1861
+	Hs
		375922 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		TANC1_HUMAN (1-1861): 0: 1673: 100.00
+	Hs
		1145101 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		TANC1_HUMAN (1-1861): 0: 1673: 100.00
+	Hs
		376087 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		ANR50_HUMAN (385-1770): 0: 687: 21.37
+	Hs
		374276 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		ANR50_HUMAN (385-1770): 0: 687: 21.37
+	Hs
		375464 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		ANK3_HUMAN (665-1857): 3.17e-143: 498: 15.06
+	Hs
		1091402 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		ANK3_HUMAN (665-1857): 3.17e-143: 498: 15.06
+	Dm
		1343481 Q962I2_DROME (4-170): 1.84e-59: 186: 51.79		Q8SWY2_DROME (569-1230): 3.08e-127: 428: 17.57
+	Hs
		376086 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		KDIS_HUMAN (1153-1294): 6.56e-31: 135: 26.67
+	Dm
		68588 RALA_DROME (4-169): 1.5e-59: 186: 52.70		A8JNM5_DROME (1026-1353): 9.55e-50: 198: 19.50
+	Hs
		1145166 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		KDIS_HUMAN (1153-1294): 6.56e-31: 135: 26.67
+	Hs
		374275 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		KDIS_HUMAN (1153-1294): 6.56e-31: 135: 26.67
+	Hs
		976655 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		KDIS_HUMAN (1153-1294): 6.56e-31: 135: 26.67
+	Hs
		956539 RAB2A_HUMAN (4-185): 5.47e-74: 223: 31.52		KDIS_HUMAN (1153-1294): 6.56e-31: 135: 26.67
+	Hs
		375418 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		ANK2_HUMAN (1494-1859): 2.6e-11: 71.6: 11.56
+	Hs
		374532 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		ANK2_HUMAN (1494-1859): 2.6e-11: 71.6: 11.56
+	Hs
		374490 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		DAPK1_HUMAN (1137-1270): 4.1e-10: 67.4: 32.09
+	Hs
		920420 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		DAPK1_HUMAN (1137-1270): 4.1e-10: 67.4: 32.09