HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1098
+	Hs
		376088 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		NEB1_HUMAN (1-1098): 2.87e-121: 401: 100.00
+	Hs
		1145167 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		NEB1_HUMAN (1-1098): 2.87e-121: 401: 100.00
+	Hs
		375465 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Hs
		1091497 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Hs
		375800 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		DLG3_HUMAN (311-1098): 6.1e-72: 258: 12.79
+	Hs
		373904 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Hs
		374556 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Hs
		374826 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		DLG3_HUMAN (311-1098): 6.1e-72: 258: 12.79
+	Hs
		976235 RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Mm
		981402 RAB1A_MOUSE (4-187): 2.9e-77: 231: 33.33		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Dm
		473610 RAS1_DROME (1-170): 2.88e-90: 263: 83.53		Q8IPP3_DROME (487-680): 5.22e-32: 138: 28.37
+	Dm
		473602 RAS1_DROME (1-170): 2.88e-90: 263: 83.53		Q24279_DROME (487-650): 6.64e-32: 137: 29.27
+	Dm
		473616 RAS1_DROME (1-170): 2.88e-90: 263: 83.53		Q95TT5_DROME (487-628): 7.75e-32: 137: 31.69
+	Hs
		375325 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		AFAD_HUMAN (419-593): 1.97e-23: 110: 30.11
+	Hs
		373859 RASN_HUMAN (1-189): 1.05e-80: 239: 100.00		AFAD_HUMAN (419-593): 1.97e-23: 110: 30.11
+	Hs
		374503 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		AFAD_HUMAN (419-593): 1.97e-23: 110: 30.11
+	Hs
		375462 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		PTN13_HUMAN (2-1014): 2.76e-18: 93.5: 11.74
+	Hs
		1090128 RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71		PTN13_HUMAN (2-1014): 2.76e-18: 93.5: 11.74
+	Hs
		375750 RASK_HUMAN (16-189): 7.11e-85: 249: 85.71		INADL_HUMAN (300-843): 1.01e-15: 84.8: 10.11
+	Hs
		374792 RASH_HUMAN (16-188): 6.69e-79: 234: 84.39		INADL_HUMAN (300-843): 1.01e-15: 84.8: 10.11