HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 1962
+	Hs
		375097 RAF1_HUMAN (1-648): 0: 652: 100.00		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		375013 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD7_HUMAN (1210-1768): 5.37e-15: 83.6: 12.63
+	Hs
		375014 RAF1_HUMAN (1-648): 0: 652: 100.00		RRBP1_HUMAN (329-778): 2.37e-09: 65.1: 13.30
+	Ce
		136795 KRAF1_CAEEL (50-627): 1.76e-151: 459: 35.95		UNC89_CAEEL (42-551): 1.46e-15: 85.7: 8.70
+	Hs
		523092 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		522749 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MUC1_HUMAN (845-1740): 1.98e-15: 84.9: 11.69
+	Hs
		522942 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Mm
		70886 SRC_MOUSE (331-607): 3.87e-105: 330: 33.10		EP300_MOUSE (789-1735): 2.76e-09: 64.7: 9.79