HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: DHX57 (Q6P158)
Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57)
Gene: DHX57

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0046872 - metal ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 1386
+	Hs
		523031 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		DHX57_HUMAN (29-1386): 0: 1536: 100.00
+	Hs
		374450 RAF1_HUMAN (1-648): 0: 652: 100.00		DHX29_HUMAN (231-1386): 0: 940: 32.11
+	Hs
		195308 RAF1_HUMAN (1-648): 0: 652: 100.00		DHX15_HUMAN (492-1331): 0: 785: 24.70
+	Hs
		224745 RAF1_HUMAN (1-648): 0: 652: 100.00		DHX16_HUMAN (287-1335): 0: 757: 19.98
+	Hs
		488695 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		DHX9_HUMAN (269-1383): 0: 894: 29.56
+	Hs
		374513 RAF1_HUMAN (1-648): 0: 652: 100.00		DHX37_HUMAN (524-1329): 0: 666: 24.53
+	Zm
		18269 A0A1D6QQC6_MAIZE (247-611): 5.88e-109: 350: 28.80		A0A1D6H4I5_MAIZE (276-1339): 0: 859: 20.82
+	Hs
		195318 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		DHX15_HUMAN (492-1331): 0: 785: 24.70