HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: LRC47 (Q8N1G4)
Leucine-rich repeat-containing protein 47
Gene: LRRC47

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 648 Hs			1 583
+	Hs
		374947 RAF1_HUMAN (1-648): 0: 652: 100.00		SYFB_HUMAN (285-575): 1.1e-56: 202: 22.80
+	Hs
		374892 RAF1_HUMAN (1-648): 0: 652: 100.00		LRC40_HUMAN (52-259): 5.3e-25: 111: 27.96
+	Hs
		374506 RAF1_HUMAN (1-648): 0: 652: 100.00		LRC8A_HUMAN (18-287): 4.49e-18: 90.1: 21.86
+	At
		95366 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		RGI4_ARATH (4-542): 4.65e-61: 220: 16.04
+	Hs
		374273 RAF1_HUMAN (1-648): 0: 652: 100.00		RSU1_HUMAN (74-237): 2.07e-13: 72.8: 34.94
+	At
		95375 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		MIK2_ARATH (1-577): 1.8e-56: 207: 15.23
+	At
		95380 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		TDR_ARATH (1-385): 5.11e-51: 191: 16.50
+	At
		85102 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		RGI2_ARATH (1-375): 2.34e-46: 177: 18.47
+	At
		83729 Y5182_ARATH (2-643): 1.52e-168: 506: 16.09		CLV1_ARATH (1-358): 4.18e-45: 173: 17.63
+	At
		83702 Y5182_ARATH (2-643): 1.52e-168: 506: 16.09		RGI3_ARATH (2-357): 2.98e-43: 168: 15.75
+	At
		95369 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		BAME1_ARATH (75-541): 5.03e-38: 152: 14.37
+	At
		84604 Y5181_ARATH (10-622): 5.26e-163: 491: 16.03		RGI3_ARATH (2-357): 2.98e-43: 168: 15.75
+	At
		83707 Y5182_ARATH (2-643): 1.52e-168: 506: 16.09		BAME1_ARATH (75-541): 5.03e-38: 152: 14.37
+	At
		1338951 Q9SNA0_ARATH (1-640): 3.53e-167: 499: 17.59		Y1571_ARATH (1-309): 6.95e-39: 154: 14.85
+	At
		84400 RLK6_ARATH (2-643): 5.27e-165: 497: 15.87		C0LGP3_ARATH (90-449): 1.28e-29: 126: 15.33
+	At
		83725 Y5182_ARATH (2-643): 1.52e-168: 506: 16.09		MIK1_ARATH (76-573): 3.45e-26: 115: 12.92
+	At
		83733 Y5189_ARATH (10-647): 2.85e-163: 492: 17.04		C0LGP3_ARATH (90-449): 1.28e-29: 126: 15.33
+	At
		95392 F4I065_ARATH (2-643): 3.97e-172: 515: 17.03		BAME2_ARATH (1-167): 5.87e-19: 93.2: 20.96
+	At
		83709 Y5182_ARATH (2-643): 1.52e-168: 506: 16.09		BAME3_ARATH (224-546): 3.67e-11: 68.2: 10.03
+	At
		1352202 Q9SNA0_ARATH (1-640): 3.53e-167: 499: 17.59		Y1723_ARATH (107-264): 8.01e-13: 73.6: 22.36