HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: MSI2H (Q96DH6)
RNA-binding protein Musashi homolog 2 (Musashi-2)
Gene: MSI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 328
+	Hs
		201649 RAF1_HUMAN (1-648): 0: 652: 100.00		MSI1H_HUMAN (1-328): 9.87e-73: 230: 66.94
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		374678 RAF1_HUMAN (1-648): 0: 652: 100.00		DAZP1_HUMAN (14-189): 4.23e-43: 154: 41.58
+	Hs
		373686 RAF1_HUMAN (1-648): 0: 652: 100.00		ROA2_HUMAN (96-206): 4.25e-26: 108: 33.33
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48
+	Hs
		453098 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		488714 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		HNRPD_HUMAN (6-289): 3.47e-55: 185: 35.21
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		523106 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MSI2H_HUMAN (1-328): 3.06e-86: 264: 100.00
+	Hs
		433441 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MSI2H_HUMAN (1-328): 3.06e-86: 264: 100.00
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48
+	Hs
		453110 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		411954 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		523014 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		RA1L2_HUMAN (9-320): 1.9e-54: 182: 28.57
+	Hs
		412217 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		RA1L2_HUMAN (9-320): 1.9e-54: 182: 28.57
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (100-190): 1.19e-13: 73.5: 17.39