Protein: FGD6
FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)

Gene: FGD6
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q6ZV73

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375645

RASK
GTPase KRas

2

20

High-throughput

0.754

High

1218376

ARHGG
Rho guanine nucleotide exchange factor 16

2

15

High-throughput

0.737

High

1256809

DBNL
Drebrin-like protein

4

19

High-throughput

0.694

High

484169

PGFRB
Platelet-derived growth factor receptor beta

1

20

High-throughput

0.691

High

987726

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.691

High

1256807

PLK2
Serine/threonine-protein kinase PLK2

1

17

High-throughput

0.691

High

691156

1433T
14-3-3 protein theta

3

20

High-throughput

0.667

High

729980

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.667

High

966508

1433G
14-3-3 protein gamma

3

20

High-throughput

0.667

High

1049462

1433F
14-3-3 protein eta

3

20

High-throughput

0.661

High

971683

1433E
14-3-3 protein epsilon

2

8

High-throughput

0.635

High

990390

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.635

High

374703

RASH
GTPase HRas

1

20

High-throughput

0.618

High

1140459

KIF14
Kinesin-like protein KIF14

1

14

High-throughput

0.618

High

1256804

KSR1
Kinase suppressor of Ras 1

1

20

High-throughput

0.618

High

1256806

KI13B
Kinesin-like protein KIF13B

1

14

High-throughput

0.618

High

730704

1433S
14-3-3 protein sigma

1

20

High-throughput

0.554

High

1228669

C102B
Coiled-coil domain-containing protein 102B

1

19

High-throughput

0.536

High

920925

CO4A4

2

3

High-throughput

0.521

High

402385

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.513

High

1243814

CTR9
RNA polymerase-associated protein CTR9 homolog

1

2

High-throughput

0.489

High

293902

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

414076

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

447140

NPM
Nucleophosmin

1

4

High-throughput

0.479

High

1004102

CXAR
Coxsackievirus and adenovirus receptor

1

6

High-throughput

0.479

High

1027544

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.470

High

1256805

H2B1H
Histone H2B type 1-H

1

3

High-throughput

0.470

High

1256810

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

106150

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

1041672

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

1

Small-scale

0.437

High

1233295

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.437

High

1256808

CING
Cingulin

1

15

High-throughput

0.437

High

1256812

KCTD3
BTB/POZ domain-containing protein KCTD3

1

15

High-throughput

0.437

High

1256811

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025