HitPredict

Interactor 1: RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase II subunit B220)
Gene: RPO21

Interactor 2: RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase II subunit B220)
Gene: RPO21

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 28585565, 20494970, 14759368
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb1_1, RNA_pol_Rpb1_1~RNA_pol_Rpb1_2, RNA_pol_Rpb1_1~RNA_pol_Rpb1_3, RNA_pol_Rpb1_1~RNA_pol_Rpb1_5, RNA_pol_Rpb1_2~RNA_pol_Rpb1_2, RNA_pol_Rpb1_2~RNA_pol_Rpb1_3, RNA_pol_Rpb1_2~RNA_pol_Rpb1_4, RNA_pol_Rpb1_2~RNA_pol_Rpb1_5, RNA_pol_Rpb1_3~RNA_pol_Rpb1_4, RNA_pol_Rpb1_3~RNA_pol_Rpb1_5, RNA_pol_Rpb1_4~RNA_pol_Rpb1_5, RNA_pol_Rpb1_5~RNA_pol_Rpb1_5
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
and 7 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1733
Sc

1 1733
+ Sc
+ Sc
+ Hp
+ Hs
+ Hs
+ Hv
+ Zm
+ At
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024