HitPredict

Interactor 1: IGHM (P01871)
Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region BOT) (Ig mu chain C region GAL) (Ig mu chain C region OU)
Gene: IGHM

Interactor 2: FNDC5 (Q8NAU1)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
Gene: FNDC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 260
+	Hs
		379757 IGHA2_HUMAN (1-346): 8.06e-41: 152: 21.70		FNDC5_HUMAN (1-260): 1.88e-174: 482: 100.00
+	Hs
		379678 IGHA1_HUMAN (21-242): 3.72e-18: 88.1: 23.01		FNDC5_HUMAN (1-260): 1.88e-174: 482: 100.00
+	Hs
		379280 IGHG1_HUMAN (5-220): 1.72e-15: 80.1: 15.98		FNDC5_HUMAN (1-260): 1.88e-174: 482: 100.00
+	Hs
		379376 IGHG2_HUMAN (7-220): 3.52e-14: 76.2: 15.21		FNDC5_HUMAN (1-260): 1.88e-174: 482: 100.00
+	Hs
		86008 IGLL5_HUMAN (96-213): 3.77e-13: 70.2: 22.88		FNDC5_HUMAN (1-260): 1.88e-174: 482: 100.00