Protein: IGLL5
Immunoglobulin lambda-like polypeptide 5 (G lambda-1) (Germline immunoglobulin lambda 1)

Gene: IGLL5
Organism: Homo sapiens
Interactions: 141
UniProt ID: B9A064

Gene Ontology (top 5):
GO:0003823 - antigen binding
GO:0016064 - immunoglobulin mediated immune response
GO:0070062 - extracellular exosome
GO:0071735 - IgG immunoglobulin complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

85949

IGLL1
Immunoglobulin lambda-like polypeptide 1

3

19

High-throughput

0.861

High

85960

CAH8
Carbonic anhydrase-related protein

3

5

High-throughput

0.770

High

86036

ULBP1
UL16-binding protein 1

2

17

High-throughput

0.726

High

49203

IGLC7
Immunoglobulin lambda constant 7

2

19

High-throughput

0.712

High

62853

POTEF
POTE ankyrin domain family member F

1

2

High-throughput

0.691

High

86024

RANB9
Ran-binding protein 9

2

4

Small-scale

0.675

High

85922

MATN2
Matrilin-2

1

8

High-throughput

0.618

High

85926

KLK10
Kallikrein-10

1

16

High-throughput

0.618

High

85930

CRLF1
Cytokine receptor-like factor 1

1

6

High-throughput

0.618

High

85953

FGFR4
Fibroblast growth factor receptor 4

1

17

High-throughput

0.618

High

85954

FGFR3
Fibroblast growth factor receptor 3

1

16

High-throughput

0.618

High

85957

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

17

High-throughput

0.618

High

85975

ANK2
Ankyrin-2

1

2

High-throughput

0.618

High

85978

SEM3B
Semaphorin-3B

1

6

High-throughput

0.618

High

85992

FNDC1
Fibronectin type III domain-containing protein 1

1

6

High-throughput

0.618

High

86008

FNDC5
Fibronectin type III domain-containing protein 5

1

5

High-throughput

0.618

High

86015

NEO1
Neogenin

1

3

High-throughput

0.618

High

85938

FINC
Fibronectin

1

5

Small-scale

0.618

High

86052

DD19B
ATP-dependent RNA helicase DDX19B

2

3

High-throughput

0.611

High

86007

ASCC1
Activating signal cointegrator 1 complex subunit 1

3

4

High-throughput

0.609

High

86020

SUSD3
Sushi domain-containing protein 3

3

2

High-throughput

0.609

High

85997

TRI68
E3 ubiquitin-protein ligase TRIM68

1

0

High-throughput

0.578

High

86056

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.578

High

85945

IGLC6
Immunoglobulin lambda constant 6

1

19

High-throughput

0.575

High

85946

IGLC3
Immunoglobulin lambda constant 3

1

19

High-throughput

0.575

High

50754

TSN11
Tetraspanin-11

2

5

High-throughput

0.574

High

85958

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

2

9

High-throughput

0.574

High

86006

FRMD1
FERM domain-containing protein 1

2

6

High-throughput

0.574

High

86022

SNX27
Sorting nexin-27

2

6

High-throughput

0.574

High

86039

DDX31
ATP-dependent DNA helicase DDX31

2

4

High-throughput

0.574

High

85980

ITA9
Integrin alpha-9

2

6

High-throughput

0.558

High

85936

EGFR
Epidermal growth factor receptor

1

16

High-throughput

0.553

High

85941

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.553

High

86000

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.553

High

85924

PLXB2
Plexin-B2

1

10

High-throughput

0.536

High

85925

LAMA5
Laminin subunit alpha-5

1

3

High-throughput

0.536

High

85947

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.536

High

85950

AATC
Aspartate aminotransferase, cytoplasmic

1

9

High-throughput

0.536

High

85961

CTNB1
Catenin beta-1

1

2

High-throughput

0.536

High

85971

HBB
Hemoglobin subunit beta

1

4

High-throughput

0.536

High

85987

T132A
Transmembrane protein 132A

1

1

High-throughput

0.536

High

85999

CSPG4
Chondroitin sulfate proteoglycan 4

1

5

High-throughput

0.536

High

86053

MA2B2
Epididymis-specific alpha-mannosidase

1

1

High-throughput

0.536

High

86057

AGRG1
Adhesion G-protein coupled receptor G1

1

6

High-throughput

0.536

High

85988

TR16L
Tripartite motif-containing protein 16-like protein

1

2

High-throughput

0.514

High

86055

PRG3
Proteoglycan 3

1

3

High-throughput

0.514

High

85943

BGLR
Beta-glucuronidase

1

0

High-throughput

0.513

High

85962

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.513

High

49386

DHR12
Dehydrogenase/reductase SDR family member 12

1

2

High-throughput

0.489

High

85923

FOXN3
Forkhead box protein N3

1

2

High-throughput

0.489

High

85931

TAD2A
Transcriptional adapter 2-alpha

1

1

High-throughput

0.489

High

85932

OR2A4
Olfactory receptor 2A4

1

6

High-throughput

0.489

High

85933

CXB5
Gap junction beta-5 protein

1

5

High-throughput

0.489

High

85934

NOE2
Noelin-2

1

3

High-throughput

0.489

High

85935

SG1D1
Secretoglobin family 1D member 1

1

5

High-throughput

0.489

High

85944

HBAT
Hemoglobin subunit theta-1

1

4

High-throughput

0.489

High

85959

CCR1
C-C chemokine receptor type 1

1

10

High-throughput

0.489

High

85963

CD151
CD151 antigen

1

5

High-throughput

0.489

High

85964

PTSS1
Phosphatidylserine synthase 1

1

4

High-throughput

0.489

High

85965

PLXA3
Plexin-A3

1

11

High-throughput

0.489

High

85966

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

2

High-throughput

0.489

High

85967

STX17
Syntaxin-17

1

4

High-throughput

0.489

High

85968

DSCR6
Protein ripply3

1

3

High-throughput

0.489

High

85969

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

2

High-throughput

0.489

High

85972

SSBP2
Single-stranded DNA-binding protein 2

1

7

High-throughput

0.489

High

85973

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

6

High-throughput

0.489

High

85976

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.489

High

85977

GABPA
GA-binding protein alpha chain

1

2

High-throughput

0.489

High

85979

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

6

High-throughput

0.489

High

85982

RUNX2
Runt-related transcription factor 2

1

2

High-throughput

0.489

High

85985

NOMO1
BOS complex subunit NOMO1

1

3

High-throughput

0.489

High

85989

CR021
UPF0711 protein C18orf21

1

6

High-throughput

0.489

High

85991

T176B
Transmembrane protein 176B

1

1

High-throughput

0.489

High

85995

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

8

High-throughput

0.489

High

85998

SFXN4
Sideroflexin-4

1

5

High-throughput

0.489

High

86001

CIR1
Corepressor interacting with RBPJ 1

1

6

High-throughput

0.489

High

86003

NRSN1
Neurensin-1

1

6

High-throughput

0.489

High

86005

RIBC1
RIB43A-like with coiled-coils protein 1

1

1

High-throughput

0.489

High

86009

TTC13
Tetratricopeptide repeat protein 13

1

6

High-throughput

0.489

High

86010

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

4

High-throughput

0.489

High

86012

RHBL4
Rhomboid-related protein 4

1

7

High-throughput

0.489

High

86014

ITLN2
Intelectin-2

1

4

High-throughput

0.489

High

86016

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

11

High-throughput

0.489

High

86017

TTC17
Tetratricopeptide repeat protein 17

1

1

High-throughput

0.489

High

86018

FKB10
Peptidyl-prolyl cis-trans isomerase FKBP10

1

3

High-throughput

0.489

High

86025

SCN2A
Sodium channel protein type 2 subunit alpha

1

7

High-throughput

0.489

High

86028

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

10

High-throughput

0.489

High

86029

EGFL8
Epidermal growth factor-like protein 8

1

7

High-throughput

0.489

High

86033

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

6

High-throughput

0.489

High

86035

CNTP3
Contactin-associated protein-like 3

1

2

High-throughput

0.489

High

86038

TM39B
Transmembrane protein 39B

1

1

High-throughput

0.489

High

86040

COE2
Transcription factor COE2

1

4

High-throughput

0.489

High

86041

MBNL1
Muscleblind-like protein 1

1

5

High-throughput

0.489

High

86042

SEM4G
Semaphorin-4G

1

8

High-throughput

0.489

High

86045

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

1

High-throughput

0.489

High

86046

SUN2
SUN domain-containing protein 2

1

3

High-throughput

0.489

High

86048

PHF11
PHD finger protein 11

1

7

High-throughput

0.489

High

86050

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

6

High-throughput

0.489

High

86054

SSUH2
Protein SSUH2 homolog

1

4

High-throughput

0.489

High

85937

CYTS
Cystatin-S

1

1

High-throughput

0.479

High

85939

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.470

High

86019

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.458

High

85940

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.437

High

85952

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.437

High

85956

PML
Protein PML

1

2

High-throughput

0.437

High

85970

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

85984

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.437

High

85986

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

85993

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

86004

RPTOR
Regulatory-associated protein of mTOR

1

2

High-throughput

0.437

High

86027

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.437

High

86034

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.437

High

86037

TRI31
E3 ubiquitin-protein ligase TRIM31

1

5

High-throughput

0.437

High

86043

RNF12
E3 ubiquitin-protein ligase RLIM

1

10

High-throughput

0.437

High

85921

E9PDS3
Integrin subunit alpha 9

1

6

High-throughput

0.407

High

85927

ANGL7
Angiopoietin-related protein 7

1

4

High-throughput

0.407

High

85929

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.407

High

85942

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

85948

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.407

High

85981

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.407

High

85996

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.407

High

86002

SULF2
Extracellular sulfatase Sulf-2

1

4

High-throughput

0.407

High

86023

CNT3B
Contactin-associated protein-like 3B

1

3

High-throughput

0.407

High

86030

PKP2
Plakophilin-2

1

2

High-throughput

0.407

High

86049

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

11

High-throughput

0.407

High

85951

EGLN
Endoglin

1

0

High-throughput

0.279

Low

86021

NAR5
Ecto-ADP-ribosyltransferase 5

1

0

High-throughput

0.279

Low

86031

USB1
U6 snRNA phosphodiesterase 1

1

0

High-throughput

0.279

Low

86051

HDAC9
Histone deacetylase 9

1

0

High-throughput

0.279

Low

85990

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

85928

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

85974

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.249

Low

85983

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low

85994

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.249

Low

86011

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.249

Low

86013

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

86044

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

86047

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.249

Low

85955

CRHBP
Corticotropin-releasing factor-binding protein

1

0

High-throughput

0.232

Low

86026

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.232

Low

86032

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025