HitPredict

Interactor 1: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Interactor 2: NUP62 (P37198)
Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62)
Gene: NUP62

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	32296183, 25910212, unassigned1304
Identification Methods	two hybrid, split luciferase complementation, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 522
+	Hs
		409020 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		NUP62_HUMAN (1-522): 3.62e-81: 264: 100.00
+	Hs
		318783 K2C75_HUMAN (1-579): 4.51e-88: 286: 53.89		NUP62_HUMAN (1-522): 3.62e-81: 264: 100.00
+	Hs
		380446 K2C6B_HUMAN (2-512): 5.16e-79: 263: 62.82		NUP62_HUMAN (1-522): 3.62e-81: 264: 100.00
+	Hs
		359469 K2C6A_HUMAN (2-512): 2.12e-75: 253: 62.43		NUP62_HUMAN (1-522): 3.62e-81: 264: 100.00
+	Hs
		517741 K2C3_HUMAN (152-497): 1.64e-62: 220: 74.71		NUP62_HUMAN (1-522): 3.62e-81: 264: 100.00