HitPredict

Interactor 1: S100B (P04271)
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)
Gene: S100B

Interactor 2: CAZA1 (P52907)
F-actin-capping protein subunit alpha-1 (CapZ alpha-1)
Gene: CAPZA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	12470955, 31837246
Identification Methods	pull down, fluorescence polarization spectroscopy, isothermal titration calorimetry
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 286
+	Hs
		638944 S100P_HUMAN (1-91): 2.35e-34: 114: 50.55		CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00
+	Hs
		615209 S10A1_HUMAN (2-89): 2.93e-33: 111: 60.23		CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00
+	Hs
		707358 S10A3_HUMAN (3-90): 1.74e-28: 100: 38.64		CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71
+	Hs
		707350 S10A5_HUMAN (2-92): 2.82e-22: 84.1: 39.56		CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00