HitPredict

Interactor 1: HBG2 (P69892)
Hemoglobin subunit gamma-2 (Gamma-2-globin) (Hb F Ggamma) (Hemoglobin gamma-2 chain) (Hemoglobin gamma-G chain)
Gene: HBG2

Interactor 2: HBA (P69905)
Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin]
Gene: HBA, HBA1;

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 32296183, unassigned1304, 881729
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Globin~Globin
Common GO terms GO:0005344 - oxygen carrier activity
GO:0005829 - cytosol
GO:0005833 - hemoglobin complex
GO:0015670 - carbon dioxide transport
GO:0015671 - oxygen transport
and 6 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 147
Hs

1 142
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Service provided by Combinatics, Japan

Last updated: 11Aug2025