HitPredict

Interactor 1: HBE (P02100)
Hemoglobin subunit epsilon (Epsilon-globin) (Hemoglobin epsilon chain)
Gene: HBE1

Interactor 2: HBA (P69905)
Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin]
Gene: HBA, HBA1;

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 32296183, unassigned1304, 11159543
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Globin~Globin
Common GO terms GO:0005344 - oxygen carrier activity
GO:0005829 - cytosol
GO:0005833 - hemoglobin complex
GO:0015670 - carbon dioxide transport
GO:0015671 - oxygen transport
and 6 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 147
Hs

1 142
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Service provided by Combinatics, Japan

Last updated: 11Aug2025