HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 671
+	Hs
		428187 TBB5_HUMAN (1-429): 0: 714: 97.44		RIPK1_HUMAN (1-671): 0: 610: 100.00
+	Hs
		201179 TBB5_HUMAN (1-429): 0: 714: 97.44		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		201419 TBB2B_HUMAN (1-430): 0: 712: 96.74		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		201171 TBB4A_HUMAN (1-427): 0: 709: 100.00		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		428113 TBB5_HUMAN (1-429): 0: 714: 97.44		RIPK4_HUMAN (14-280): 7.4e-33: 137: 34.31
+	Hs
		883508 TBB3_HUMAN (1-444): 0: 714: 91.44		RIPK4_HUMAN (14-280): 7.4e-33: 137: 34.31
+	Hs
		883476 TBB4B_HUMAN (1-427): 0: 713: 98.60		RIPK4_HUMAN (14-280): 7.4e-33: 137: 34.31
+	Hs
		1037393 TBB3_HUMAN (1-444): 0: 714: 91.44		Q9H4D1_HUMAN (14-281): 1.82e-32: 135: 34.18
+	Hs
		428431 TBB5_HUMAN (1-429): 0: 714: 97.44		Q9H4D1_HUMAN (14-281): 1.82e-32: 135: 34.18
+	Hs
		883632 TBB2B_HUMAN (1-430): 0: 712: 96.74		RIPK4_HUMAN (14-280): 7.4e-33: 137: 34.31
+	Hs
		428522 TBB5_HUMAN (1-429): 0: 714: 97.44		RIPK3_HUMAN (18-286): 1.57e-32: 134: 33.33
+	Hs
		933974 TBB4B_HUMAN (1-427): 0: 713: 98.60		Q9H4D1_HUMAN (14-281): 1.82e-32: 135: 34.18
+	Hs
		1313672 TBB2B_HUMAN (1-430): 0: 712: 96.74		Q9H4D1_HUMAN (14-281): 1.82e-32: 135: 34.18
+	Hs
		1313700 TBB2B_HUMAN (1-430): 0: 712: 96.74		RIPK3_HUMAN (18-286): 1.57e-32: 134: 33.33
+	Hs
		883510 TBB2A_HUMAN (1-430): 0: 709: 96.28		RIPK4_HUMAN (14-280): 7.4e-33: 137: 34.31
+	Hs
		1046578 TBB2A_HUMAN (1-430): 0: 709: 96.28		Q9H4D1_HUMAN (14-281): 1.82e-32: 135: 34.18
+	Hs
		201743 TBB5_HUMAN (1-429): 0: 714: 97.44		RIPK2_HUMAN (60-306): 4.47e-30: 127: 32.96
+	Hs
		201824 TBB2B_HUMAN (1-430): 0: 712: 96.74		RIPK2_HUMAN (60-306): 4.47e-30: 127: 32.96
+	Hs
		411549 TBB5_HUMAN (1-429): 0: 714: 97.44		LCK_HUMAN (23-289): 1.31e-27: 119: 31.87
+	Hs
		411668 TBB4B_HUMAN (1-427): 0: 713: 98.60		LCK_HUMAN (23-289): 1.31e-27: 119: 31.87