HitPredict

Interactor 1: H2B2 (P02294)
Histone H2B.2
Gene: HTB2

Interactor 2: PDP3 (Q06188)
NuA3 HAT complex component PDP3 (PWWP domain-containing protein YLR455W)
Gene: PDP3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	16554755, 25104842, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 304
+	Sc
		381271 H2B1_YEAST (1-131): 4.06e-44: 142: 96.95		PDP3_YEAST (1-304): 2.21e-121: 351: 100.00
+	Sp
		237542 H2B1_SCHPO (3-130): 1.86e-43: 140: 81.25		PDP1_SCHPO (5-290): 3.74e-87: 266: 21.73
+	Hs
		1162946 H2B2E_HUMAN (7-129): 4.64e-47: 149: 70.40		GLYR1_HUMAN (4-184): 2.56e-64: 213: 19.02
+	Hs
		980809 H2B1C_HUMAN (7-129): 9.05e-47: 148: 70.40		GLYR1_HUMAN (4-184): 2.56e-64: 213: 19.02
+	Hs
		355536 H2B2E_HUMAN (7-129): 4.64e-47: 149: 70.40		NSD2_HUMAN (3-159): 1.75e-11: 66.8: 13.29
+	Hs
		355476 H2B1C_HUMAN (7-129): 9.05e-47: 148: 70.40		NSD2_HUMAN (3-159): 1.75e-11: 66.8: 13.29
+	Hs
		1163187 H2B2E_HUMAN (7-129): 4.64e-47: 149: 70.40		NSD3_HUMAN (5-199): 4.84e-11: 65.7: 15.24
+	Hs
		754975 H2B1B_HUMAN (7-129): 1.3e-46: 148: 69.60		NSD3_HUMAN (5-199): 4.84e-11: 65.7: 15.24
+	Hs
		981070 H2B1C_HUMAN (7-129): 9.05e-47: 148: 70.40		NSD3_HUMAN (5-199): 4.84e-11: 65.7: 15.24
+	Hs
		1163142 H2B2E_HUMAN (7-129): 4.64e-47: 149: 70.40		NSD1_HUMAN (9-119): 3.02e-10: 63.4: 19.47
+	Hs
		1372270 H2B1H_HUMAN (7-129): 4.85e-47: 149: 70.40		NSD1_HUMAN (9-119): 3.02e-10: 63.4: 19.47
+	Hs
		981018 H2B1C_HUMAN (7-129): 9.05e-47: 148: 70.40		NSD1_HUMAN (9-119): 3.02e-10: 63.4: 19.47