HitPredict

Interactor 1: HLAA (P04439)
HLA class I histocompatibility antigen, A alpha chain (Human leukocyte antigen A) (HLA-A)
Gene: HLA-A

Interactor 2: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~Lectin_C, Lectin_C~MHC_I
Common GO terms	GO:0006955 - immune response GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 222
+	Hs
		382559 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60
+	Hs
		532886 HLAE_HUMAN (20-357): 5.1e-143: 411: 78.99		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		532899 HLAF_HUMAN (4-348): 3.64e-141: 406: 80.29		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		354602 HLAB_HUMAN (1-362): 3.05e-157: 447: 85.64		CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60
+	Hs
		488269 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		CLC4G_HUMAN (38-221): 2.03e-39: 138: 18.62
+	Hs
		488420 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60
+	Hs
		674000 HLAF_HUMAN (4-348): 3.64e-141: 406: 80.29		CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60
+	Hs
		533033 HMR1_HUMAN (1-348): 1.11e-111: 330: 36.29		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		570381 HLAG_HUMAN (1-338): 2.35e-151: 431: 82.84		MRC2_HUMAN (109-217): 3.74e-09: 58.3: 21.10
+	Hs
		1278673 HMR1_HUMAN (1-348): 1.11e-111: 330: 36.29		CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60