HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: UBP48 (Q86UV5)
Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48)
Gene: USP48

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	25921289, 33903120
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 1035
+	Hs
		385638 NTRK1_HUMAN (1-796): 0: 621: 100.00		UBP36_HUMAN (15-525): 2.42e-103: 351: 18.10
+	Hs
		385300 NTRK1_HUMAN (1-796): 0: 621: 100.00		UBP7_HUMAN (66-487): 5.02e-100: 341: 26.05
+	Hs
		385299 NTRK1_HUMAN (1-796): 0: 621: 100.00		USP9X_HUMAN (43-477): 4.66e-92: 325: 23.27
+	Hs
		609458 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		USP9X_HUMAN (43-477): 4.66e-92: 325: 23.27
+	Hs
		385356 NTRK1_HUMAN (1-796): 0: 621: 100.00		UBP47_HUMAN (83-468): 6.67e-35: 147: 26.48
+	Hs
		131649 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		USP9Y_HUMAN (43-477): 3.56e-99: 347: 23.67
+	Hs
		435718 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		USP9X_HUMAN (43-477): 4.66e-92: 325: 23.27
+	Hs
		666631 LTK_HUMAN (502-790): 3.09e-60: 221: 41.64		USP9X_HUMAN (43-477): 4.66e-92: 325: 23.27