HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TNR6 (P25445)
Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
Gene: FAS

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34917906, 18443131
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0042981 - regulation of apoptotic process GO:0043065 - positive regulation of apoptotic process GO:0043066 - negative regulation of apoptotic process GO:0065003 - protein-containing complex assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 335
+	Hs
		124655 P53_HUMAN (1-393): 0: 619: 100.00		TR11B_HUMAN (42-302): 2.68e-66: 215: 20.07
+	Hs
		385941 P53_HUMAN (1-393): 0: 619: 100.00		TNR16_HUMAN (44-244): 4.15e-42: 153: 18.23
+	Hs
		632400 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		TNR6_HUMAN (1-335): 2.61e-113: 333: 100.00
+	Hs
		154293 P53_HUMAN (1-393): 0: 619: 100.00		TR10B_HUMAN (42-216): 2.84e-31: 123: 21.91
+	Hs
		386818 P53_HUMAN (1-393): 0: 619: 100.00		LAMA4_HUMAN (34-233): 2.06e-14: 76.5: 13.86