Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.750

The method score is based on:

Property Details
Experiments 15538975, 9732264, 9393873, 9724739, 19651615, 18813780, 11108663, 12514174, 10706102
Identification Methods pull down, affinity chromatography technology, enzymatic study, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
and 6 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 393
Hs

1 427
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Last updated: 15 Jul 2024