HitPredict

Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16889989
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030097 - hemopoiesis
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2419 Hs			1 616
+	Hs
		555611 ACTN1_HUMAN (1927-2418): 6.44e-50: 195: 26.84		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		695516 PLEC_HUMAN (359-2399): 3.5e-41: 170: 10.02		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		695414 SPTN1_HUMAN (2-1581): 5.76e-39: 162: 15.98		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		174708 SPTN2_HUMAN (953-2402): 1.23e-27: 125: 14.36		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		695232 SPTB2_HUMAN (1473-2375): 3.14e-25: 117: 17.59		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		695474 GOGB1_HUMAN (1568-2404): 6.77e-16: 87: 10.11		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		695259 DYST_HUMAN (248-1223): 4.71e-15: 84.4: 10.37		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		694907 CENPF_HUMAN (1-405): 1.31e-12: 76.2: 9.38		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		696869 MACF1_HUMAN (50-1190): 1.36e-11: 72.8: 11.14		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		224628 ACTN4_HUMAN (1728-2169): 1.64e-11: 72: 23.31		RFA1_HUMAN (1-616): 0: 781: 100.00