HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

The method score is based on:

Property	Details
Experiments	10961991, 23825024, 32807901, 20534433, 19684601, 16732283
Identification Methods	two hybrid, affinity chromatography technology, pull down, comigration in sds page
Interaction Type	direct interaction, physical association, covalent binding

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol GO:0016605 - PML body and 4 others more... GO:0019899 - enzyme binding GO:0031625 - ubiquitin protein ligase binding GO:0045892 - negative regulation of DNA-templated transcription GO:0050821 - protein stabilization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	101

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024