HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RN128 (Q8TEB7)
E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (GRAIL) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128)
Gene: RNF128

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	31715145, 23370271
Identification Methods	enzymatic study, pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 428
+	Mm
		356888 P53_MOUSE (1-393): 0: 589: 77.35		RN128_MOUSE (1-428): 4.74e-148: 429: 95.33
+	Hs
		386915 P53_HUMAN (1-393): 0: 619: 100.00		RNF43_HUMAN (53-406): 2.06e-51: 186: 17.69
+	Hs
		387017 P53_HUMAN (1-393): 0: 619: 100.00		SYVN1_HUMAN (31-396): 6.32e-39: 149: 13.93
+	Dm
		1279545 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		HRD1_DROME (31-371): 3.9e-38: 147: 14.08
+	Dm
		1213224 Q8IMZ4_DROME (124-325): 1.54e-78: 252: 24.31		Q9VGI6_DROME (269-321): 4.6e-09: 60.8: 43.40
+	Dm
		1341773 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		Q9VGI6_DROME (269-321): 4.6e-09: 60.8: 43.40