HitPredict

Interactor 1: MLC2 (P54357)
Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain)
Gene: Mlc-c

Interactor 2: Q59E59 (Q59E59)
Zipper, isoform D
Gene: zip

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EF-hand_6~IQ, EF-hand_6~Myosin_head, EF-hand_7~IQ, EF-hand_7~Myosin_head, EF-hand_7~Myosin_N, EF-hand_7~Myosin_tail_1
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 147 Dm			1 2016
+	Ce
		110227 CALM_CAEEL (3-146): 5.11e-46: 148: 44.22		G5EBY3_CAEEL (64-1990): 0: 1385: 47.33
+	Dm
		929129 MLC2_DROME (1-147): 1.46e-42: 139: 100.00		MYSN_DROME (1-2016): 0: 1191: 96.94
+	Hs
		773142 MYL6_HUMAN (1-147): 4.17e-56: 174: 53.64		MYH10_HUMAN (1029-2014): 9.79e-60: 230: 18.34
+	Gg
		387172 MYL6_CHICK (1-147): 9.12e-55: 170: 54.31		MYH11_CHICK (1120-2015): 7.62e-59: 227: 18.72
+	Hs
		772704 MYL6_HUMAN (1-147): 4.17e-56: 174: 53.64		MYH9_HUMAN (1110-2016): 1.01e-56: 220: 16.52
+	Hs
		776792 MYL6_HUMAN (1-147): 4.17e-56: 174: 53.64		MYH11_HUMAN (1096-2016): 5.14e-56: 218: 16.27
+	Hs
		573929 MYL6B_HUMAN (3-146): 1.31e-48: 156: 53.38		MYH10_HUMAN (1029-2014): 9.79e-60: 230: 18.34
+	Hs
		573928 MYL6B_HUMAN (3-146): 1.31e-48: 156: 53.38		MYH9_HUMAN (1110-2016): 1.01e-56: 220: 16.52
+	Hs
		952590 MYL6_HUMAN (1-147): 4.17e-56: 174: 53.64		MYH14_HUMAN (1162-2016): 1.43e-50: 200: 15.76
+	Mm
		483499 MYL3_MOUSE (4-146): 4.01e-40: 135: 49.66		MYH6_MOUSE (1029-2015): 4.12e-62: 238: 16.67
+	Hs
		437572 MYL1_HUMAN (4-146): 3.12e-42: 140: 53.06		MYH10_HUMAN (1029-2014): 9.79e-60: 230: 18.34
+	Hs
		472238 MYL3_HUMAN (4-146): 8.75e-40: 134: 48.99		MYH10_HUMAN (1029-2014): 9.79e-60: 230: 18.34
+	Hs
		692660 CALL3_HUMAN (3-146): 2.79e-43: 141: 42.18		MYH9_HUMAN (1110-2016): 1.01e-56: 220: 16.52
+	Hs
		573968 MYL6B_HUMAN (3-146): 1.31e-48: 156: 53.38		MYH14_HUMAN (1162-2016): 1.43e-50: 200: 15.76
+	Hs
		472237 MYL3_HUMAN (4-146): 8.75e-40: 134: 48.99		MYH9_HUMAN (1110-2016): 1.01e-56: 220: 16.52
+	Ce
		386959 MLE_CAEEL (1-147): 5.6e-32: 112: 42.67		MYO1_CAEEL (1083-2015): 3.71e-60: 231: 15.08
+	Hs
		472247 MYL3_HUMAN (4-146): 8.75e-40: 134: 48.99		MYH14_HUMAN (1162-2016): 1.43e-50: 200: 15.76
+	Ce
		386947 MLE_CAEEL (1-147): 5.6e-32: 112: 42.67		MYO4_CAEEL (1116-2016): 1.29e-56: 220: 17.02
+	Ce
		556462 MLE_CAEEL (1-147): 5.6e-32: 112: 42.67		MYO3_CAEEL (775-1636): 1.92e-41: 170: 16.00