HitPredict

Interactor 1: C1QA (P02745)
Complement C1q subcomponent subunit A
Gene: C1QA

Interactor 2: RAGE (Q15109)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: AGER

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22386596
Identification Methods	unspecified method, surface plasmon resonance array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001540 - amyloid-beta binding GO:0001774 - microglial cell activation GO:0005576 - extracellular region GO:0048143 - astrocyte activation GO:0098794 - postsynapse
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 404
+	Hs
		388715 C1QB_HUMAN (10-243): 1.5e-46: 156: 38.14		RAGE_HUMAN (1-404): 1.78e-71: 231: 100.00
+	Hs
		388778 C1QC_HUMAN (25-243): 1.1e-45: 154: 38.46		RAGE_HUMAN (1-404): 1.78e-71: 231: 100.00
+	Hs
		1366071 C1QT7_HUMAN (21-242): 3.84e-45: 154: 31.65		PXDN_HUMAN (172-403): 5.1e-25: 109: 13.42
+	Hs
		505801 C1T9A_HUMAN (15-156): 3.32e-24: 100: 22.67		L1CAM_HUMAN (8-400): 3.52e-14: 76.6: 10.70
+	Hs
		505839 C1T9A_HUMAN (15-156): 3.32e-24: 100: 22.67		TITIN_HUMAN (210-404): 5.96e-09: 60.4: 15.87