Interactor 1: A2GL (P02750)
Leucine-rich alpha-2-glycoprotein (LRG)
Gene: LRG1
Interactor 2: TGFR2 (P37173)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: TGFBR2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.681 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23868260 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_8~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0010718 - positive regulation of epithelial to mesenchymal transition GO:0016020 - membrane and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
