HitPredict

Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: TIMP2 (P16035)
Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2)
Gene: TIMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39238192
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002020 - protease binding GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0031012 - extracellular matrix
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2477 Hs			1 220
+	Hs
		590934 COCA1_HUMAN (578-1293): 7.17e-62: 238: 18.70		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		1052172 COEA1_HUMAN (588-900): 8.81e-24: 113: 18.63		TIMP4_HUMAN (24-220): 3.32e-107: 309: 49.75
+	Hs
		469658 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		575772 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		469695 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		TIMP4_HUMAN (24-220): 3.32e-107: 309: 49.75
+	Hs
		469666 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		TIMP3_HUMAN (10-220): 1.97e-95: 278: 44.19
+	Hs
		369992 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		TIMP1_HUMAN (10-203): 5.84e-86: 255: 42.29
+	Hs
		369998 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		TIMP1_HUMAN (10-203): 5.84e-86: 255: 42.29