HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: MK10 (P53779)
Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)
Gene: MAPK10

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.759

Property	Details
Experiments	9596579, 10101227, 19527717, 8654373, 16824735, 16007099, 21988832, 22327296, 1922387
Identification Methods	enzymatic study, pull down, two hybrid, protein kinase assay, biochemical, in-gel kinase assay
Interaction Type	direct interaction, physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 331 Hs			1 464
+	Rn
		567365 JUN_RAT (1-331): 3.98e-86: 264: 94.01		MK10_RAT (1-464): 0: 516: 99.14
+	Hs
		401593 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		MK09_HUMAN (39-464): 1.45e-163: 469: 83.80
+	Hs
		401592 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		MK08_HUMAN (39-464): 5.15e-162: 465: 90.87
+	Rn
		567364 JUN_RAT (1-331): 3.98e-86: 264: 94.01		MK09_RAT (39-464): 2.57e-162: 466: 83.10
+	Rn
		567363 JUN_RAT (1-331): 3.98e-86: 264: 94.01		MK08_RAT (39-448): 3.49e-156: 450: 90.02
+	Mm
		404155 JUN_MOUSE (1-331): 5.76e-86: 263: 94.61		MK08_MOUSE (39-419): 3e-151: 437: 91.86
+	Hs
		568080 JUND_HUMAN (5-331): 5.93e-47: 163: 45.86		MK10_HUMAN (1-464): 0: 517: 100.00
+	Hs
		566735 JUNB_HUMAN (1-331): 3.94e-63: 205: 43.89		MK09_HUMAN (39-464): 1.45e-163: 469: 83.80
+	Hs
		566734 JUNB_HUMAN (1-331): 3.94e-63: 205: 43.89		MK08_HUMAN (39-464): 5.15e-162: 465: 90.87
+	Hs
		402080 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		MK14_HUMAN (42-408): 2.57e-133: 390: 45.95
+	Hs
		568074 JUND_HUMAN (5-331): 5.93e-47: 163: 45.86		MK09_HUMAN (39-464): 1.45e-163: 469: 83.80
+	Hs
		568073 JUND_HUMAN (5-331): 5.93e-47: 163: 45.86		MK08_HUMAN (39-464): 5.15e-162: 465: 90.87
+	Hs
		547743 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		MK09_HUMAN (39-464): 1.45e-163: 469: 83.80
+	Hs
		547742 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		MK08_HUMAN (39-464): 5.15e-162: 465: 90.87
+	Hs
		173828 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		MK13_HUMAN (43-411): 3.49e-133: 390: 45.55
+	Hs
		401456 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		MK03_HUMAN (58-397): 1.2e-84: 266: 42.12
+	Hs
		401473 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		MK01_HUMAN (58-397): 8.71e-85: 266: 42.98
+	Hs
		568066 JUND_HUMAN (5-331): 5.93e-47: 163: 45.86		MK01_HUMAN (58-397): 8.71e-85: 266: 42.98
+	Hs
		547709 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		MK03_HUMAN (58-397): 1.2e-84: 266: 42.12
+	Hs
		547713 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		MK01_HUMAN (58-397): 8.71e-85: 266: 42.98