Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28330616, 28675297
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_beta~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0030027 - lamellipodium
GO:0030032 - lamellipodium assembly
GO:0043197 - dendritic spine
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 798
Hs

1 1216
+ Mm
+ Dm
+ Hs
+ Dm
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024