HitPredict

Interactor 1: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Interactor 2: TIMP2 (P16035)
Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2)
Gene: TIMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39238192
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 220
+	Hs
		590903 KRT81_HUMAN (79-568): 3.35e-83: 272: 45.23		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		566327 K2C5_HUMAN (1-496): 1.95e-79: 264: 64.72		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		407248 K2C6B_HUMAN (2-512): 7e-78: 260: 62.82		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		385234 K2C6A_HUMAN (2-512): 1.41e-74: 251: 62.43		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00
+	Hs
		590949 KRT82_HUMAN (72-495): 1.37e-74: 250: 50.94		TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00