HitPredict

Interactor 1: TIMP2 (P16035)
Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2)
Gene: TIMP2

Interactor 2: KRT81 (Q14533)
Keratin, type II cuticular Hb1 (Hair keratin K2.9) (Keratin, hair, basic, 1) (Keratin-81) (K81) (Metastatic lymph node 137 gene protein) (MLN 137) (Type II hair keratin Hb1) (Type-II keratin Kb21) (ghHKb1) (ghHb1)
Gene: KRT81

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39238192
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 220 Hs			1 505
+	Hs
		407382 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K2C1_HUMAN (70-431): 2.09e-127: 387: 54.67
+	Hs
		590949 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		KRT82_HUMAN (4-503): 1.78e-84: 272: 54.03
+	Hs
		407248 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K2C6B_HUMAN (73-420): 1.44e-74: 247: 58.29
+	Hs
		566327 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K2C5_HUMAN (73-420): 7.58e-74: 246: 59.43
+	Hs
		385234 TIMP2_HUMAN (1-220): 2.85e-111: 319: 100.00		K2C6A_HUMAN (73-420): 4.44e-73: 243: 58.57
+	Hs
		370015 TIMP1_HUMAN (10-203): 5.84e-86: 255: 42.29		KRT35_HUMAN (1-417): 1.9e-69: 230: 26.56