HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: ERBIN (Q96RT1)
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)
Gene: ERBIN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_8~PK_Tyr_Ser-Thr, LRR_8~SH2
Common GO terms	GO:0005102 - signaling receptor binding GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 1412
+	Hs
		433956 LYN_HUMAN (1-509): 0: 582: 62.72		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		411718 LCK_HUMAN (1-509): 0: 661: 100.00		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		411699 LCK_HUMAN (1-509): 0: 661: 100.00		FLII_HUMAN (94-449): 1.19e-20: 101: 28.27
+	Hs
		433758 LYN_HUMAN (1-509): 0: 582: 62.72		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		433978 LYN_HUMAN (1-509): 0: 582: 62.72		LRRC1_HUMAN (311-709): 1.39e-23: 108: 15.97