Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (Ser-473 kinase) (S473K) (p460)
Gene: PRKDC
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11751391, 35474131, 9744860, 25362358, 10608806, 10601022, 8940078, 12756247, 9679063, 15355354, 19918261, 9363941, 10713094 |
| Identification Methods | affinity chromatography technology, enzymatic study, unspecified method |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000785 - chromatin GO:0001756 - somitogenesis GO:0002326 - B cell lineage commitment GO:0002360 - T cell lineage commitment GO:0005634 - nucleus and 15 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
