Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 28855742, 20974803
Identification Methods affinity chromatography technology, pull down, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~Pkinase
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006915 - apoptotic process
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 297
Hs

1 440
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024