Interactor 1: GELS (P06396)
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)
Gene: GSN

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.818

The method score is based on:

Property Details
Experiments 10583954, 8395021, 10854330
Identification Methods x-ray crystallography
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Gelsolin
Common GO terms GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
GO:0015629 - actin cytoskeleton
GO:0030027 - lamellipodium
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 782
Hs

1 377
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Last updated: 15 Jul 2024