HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: GGYF2 (Q6Y7W6)
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)
Gene: GIGYF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23443559
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0031571 - mitotic G1 DNA damage checkpoint signaling GO:0032991 - protein-containing complex GO:0035264 - multicellular organism growth
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1299
+	Hs
		414425 P53_HUMAN (1-393): 0: 619: 100.00		KI16B_HUMAN (728-1025): 1.37e-33: 143: 22.98
+	Hs
		414928 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (410-1295): 3.1e-32: 139: 10.35
+	Hs
		413308 P53_HUMAN (1-393): 0: 619: 100.00		MYH9_HUMAN (450-1298): 2.53e-22: 106: 10.29
+	Hs
		413870 P53_HUMAN (1-393): 0: 619: 100.00		PLEC_HUMAN (141-969): 1.17e-15: 85.2: 10.37
+	Hs
		413132 P53_HUMAN (1-393): 0: 619: 100.00		DESP_HUMAN (612-1126): 9.08e-13: 75.5: 14.07
+	Hs
		413774 P53_HUMAN (1-393): 0: 619: 100.00		ROCK1_HUMAN (613-1073): 5.1e-10: 66.3: 11.02
+	Hs
		414821 P53_HUMAN (1-393): 0: 619: 100.00		MYH13_HUMAN (604-1059): 1.01e-09: 65.5: 11.38
+	Hs
		1008645 P63_HUMAN (28-363): 2.36e-145: 429: 42.11		MAP1A_HUMAN (308-982): 5.51e-34: 145: 11.77
+	Dm
		68225 Q9N6D8_DROME (124-325): 3.12e-77: 245: 24.31		A8DYA3_DROME (757-994): 5.86e-11: 69.7: 18.22