HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.678

The method score is based on:

Property Details
Experiments 11596110, 8552662, 18628207
Identification Methods pull down, far western blotting, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 928
Hs

1 345
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024