Interactor 1: SIR2 (P06700)
NAD-dependent histone deacetylase SIR2 (EC 2.3.1.286) (Regulatory protein SIR2) (Silent information regulator 2)
Gene: SIR2

Interactor 2: MCM3 (P24279)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3)
Gene: MCM3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 19064704
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030466 - silent mating-type cassette heterochromatin formation
GO:0031509 - subtelomeric heterochromatin formation
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 562
Sc

1 971
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024