HitPredict

Interactor 1: SIR2 (P06700)
NAD-dependent histone deacetylase SIR2 (EC 2.3.1.286) (Regulatory protein SIR2) (Silent information regulator 2)
Gene: SIR2

Interactor 2: TOF2 (Q02208)
Topoisomerase 1-associated factor 2
Gene: TOF2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	17043313, 37968396, 20489023
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000183 - rDNA heterochromatin formation GO:0005730 - nucleolus
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 562 Sc			1 771
+	Sc
		416231 SIR2_YEAST (1-562): 0: 847: 100.00		NET1_YEAST (4-236): 1.05e-82: 288: 30.90