HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: SENP3 (Q9H4L4)
Sentrin-specific protease 3 (EC 3.4.22.-) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3)
Gene: SENP3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	33961781, 18259216, 21326211
Identification Methods	affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 574
+	Hs
		271411 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		SENP3_HUMAN (1-574): 0: 683: 100.00
+	Hs
		418548 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		SENP5_HUMAN (237-572): 8.14e-102: 326: 45.99
+	Hs
		271384 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		SENP5_HUMAN (237-572): 8.14e-102: 326: 45.99