Protein: GNA13
Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13)

Gene: GNA13
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q14344

Gene Ontology (top 5):
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001701 - in utero embryonic development
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005085 - guanyl-nucleotide exchange factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1125910

ARHG1
Rho guanine nucleotide exchange factor 1

5

19

Small-scale

0.922

High

640512

TA2R
Thromboxane A2 receptor

5

20

Small-scale

0.909

High

177380

ARHGB
Rho guanine nucleotide exchange factor 11

3

20

Small-scale

0.827

High

1125940

ARHGC
Rho guanine nucleotide exchange factor 12

3

14

Small-scale

0.827

High

1125934

RIC8A
Chaperone Ric-8A

2

14

Small-scale

0.808

High

1040969

GNA12
Guanine nucleotide-binding protein subunit alpha-12

2

13

High-throughput

0.789

High

669387

PAR1
Proteinase-activated receptor 1

2

19

Small-scale

0.776

High

638194

S1PR1
Sphingosine 1-phosphate receptor 1

1

20

High-throughput

0.691

High

1125932

GPR35
G-protein coupled receptor 35

1

20

High-throughput

0.691

High

733746

CXCR5
C-X-C chemokine receptor type 5

1

14

Small-scale

0.665

High

956863

CXCR4
C-X-C chemokine receptor type 4

1

18

Small-scale

0.665

High

580768

PVR
Poliovirus receptor

1

0

High-throughput

0.656

High

192037

RGS16
Regulator of G-protein signaling 16

1

20

Small-scale

0.647

High

893556

GBG4

2

20

High-throughput

0.628

High

992429

GBG3

2

20

High-throughput

0.628

High

533820

MCF2
Proto-oncogene DBL

1

2

Small-scale

0.618

High

641907

DRD5
D(1B) dopamine receptor

1

10

Small-scale

0.618

High

733349

CCR1
C-C chemokine receptor type 1

1

18

High-throughput

0.618

High

989842

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

12

High-throughput

0.618

High

1125898

ARG28
Rho guanine nucleotide exchange factor 28

1

13

Small-scale

0.618

High

1125939

TA2R7
Taste receptor type 2 member 7

1

1

High-throughput

0.618

High

948062

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

2

20

Small-scale

0.611

High

962042

RHOA
Transforming protein RhoA

2

15

High-throughput

0.611

High

1125906

T185A
Transmembrane protein 185A

2

3

High-throughput

0.611

High

1125922

AASD1
Alanyl-tRNA editing protein Aarsd1

2

4

High-throughput

0.611

High

1125935

ANLN
Anillin

2

8

High-throughput

0.611

High

1125941

GBG12

2

20

High-throughput

0.611

High

1125900

S2541
Mitochondrial carrier protein SCaMC-3L

3

3

High-throughput

0.609

High

893569

GBG10

2

20

High-throughput

0.601

High

911834

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

2

2

High-throughput

0.601

High

948827

CD81
CD81 antigen

2

7

Small-scale

0.601

High

983481

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

2

20

High-throughput

0.601

High

1125946

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

2

20

High-throughput

0.601

High

1125951

SGT1
Protein SGT1 homolog

2

5

High-throughput

0.601

High

241674

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

1125917

PKH4B
Pleckstrin homology domain-containing family G member 4B

1

2

High-throughput

0.575

High

299713

AKAP3
A-kinase anchor protein 3

1

0

Small-scale

0.549

High

767432

RADI
Radixin

1

0

Small-scale

0.549

High

231702

PEX1
Peroxisomal ATPase PEX1

1

6

High-throughput

0.536

High

537153

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.536

High

902925

DUS3
Dual specificity protein phosphatase 3

1

15

High-throughput

0.536

High

925533

MOT1
Monocarboxylate transporter 1

1

6

High-throughput

0.536

High

932071

EPHA4
Ephrin type-A receptor 4

1

7

High-throughput

0.536

High

984112

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

20

High-throughput

0.536

High

992413

GBG1
Guanine nucleotide-binding protein G(T) subunit gamma-T1

1

20

High-throughput

0.536

High

992440

GBG5

1

20

High-throughput

0.536

High

1125885

OTUD3
OTU domain-containing protein 3

1

3

High-throughput

0.536

High

1125891

SPSB3
SPRY domain-containing SOCS box protein 3

1

8

High-throughput

0.536

High

1125897

CMIP
C-Maf-inducing protein

1

2

High-throughput

0.536

High

1125901

TEX29
Testis-expressed protein 29

1

1

High-throughput

0.536

High

1125905

UXS1
UDP-glucuronic acid decarboxylase 1

1

1

High-throughput

0.536

High

1125929

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

20

High-throughput

0.536

High

1125936

DUS22
Dual specificity protein phosphatase 22

1

14

High-throughput

0.536

High

1125942

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

1

High-throughput

0.536

High

1125948

STX8
Syntaxin-8

1

1

High-throughput

0.536

High

1125949

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.536

High

124779

AIP
AH receptor-interacting protein

1

6

Small-scale

0.527

High

1106534

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.525

High

250611

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

862649

UTRN
Utrophin

1

0

High-throughput

0.513

High

914535

EFNA5
Ephrin-A5

1

0

High-throughput

0.513

High

1125894

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

1125914

ISOC1
Isochorismatase domain-containing protein 1

1

0

High-throughput

0.513

High

1125916

MUS81
Structure-specific endonuclease subunit MUS81

1

0

High-throughput

0.513

High

1125919

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.513

High

1125923

RAMAC
RNA guanine-N7 methyltransferase activating subunit

1

0

High-throughput

0.513

High

1125928

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.513

High

1125931

FANCE
Fanconi anemia group E protein

1

0

High-throughput

0.513

High

1125945

DPOG2
DNA polymerase subunit gamma-2

1

0

High-throughput

0.513

High

1125947

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.513

High

1125950

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

0

High-throughput

0.513

High

1125953

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

436667

KPCB
Protein kinase C beta type

1

8

Small-scale

0.501

High

556081

CADH1
Cadherin-1

1

5

Small-scale

0.501

High

605679

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

5

Small-scale

0.501

High

618251

CADH2
Cadherin-2

1

5

Small-scale

0.501

High

916658

PPP5
Serine/threonine-protein phosphatase 5

1

3

Small-scale

0.501

High

1034992

KPCE
Protein kinase C epsilon type

1

6

Small-scale

0.501

High

1051926

KPCD
Protein kinase C delta type

1

8

Small-scale

0.501

High

1125937

GIMA4
GTPase IMAP family member 4

1

0

High-throughput

0.493

High

1125907

WDR36
WD repeat-containing protein 36

1

4

High-throughput

0.489

High

342870

HERC2
E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.479

High

375518

RASK
GTPase KRas

1

11

High-throughput

0.479

High

411925

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

466251

RHOC
Rho-related GTP-binding protein RhoC

1

15

High-throughput

0.479

High

466668

GLI1
Zinc finger protein GLI1

1

1

Small-scale

0.479

High

478684

HXB5
Homeobox protein Hox-B5

1

4

High-throughput

0.479

High

568807

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

2

Small-scale

0.479

High

588690

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

695449

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

728230

AKT1
RAC-alpha serine/threonine-protein kinase

1

7

High-throughput

0.479

High

777278

AHR
Aryl hydrocarbon receptor

1

2

Small-scale

0.479

High

862131

YAP1
Transcriptional coactivator YAP1

1

9

High-throughput

0.479

High

953446

RAC3
Ras-related C3 botulinum toxin substrate 3

1

15

High-throughput

0.479

High

978007

RHOB
Rho-related GTP-binding protein RhoB

1

16

High-throughput

0.479

High

1086215

TFCP2
Alpha-globin transcription factor CP2

1

8

High-throughput

0.479

High

1096685

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.479

High

1125282

FAK2
Protein-tyrosine kinase 2-beta

1

6

Small-scale

0.479

High

1125880

CUL7
Cullin-7

1

1

High-throughput

0.479

High

1125881

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1125883

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

Small-scale

0.479

High

1125884

FRPD1
FERM and PDZ domain-containing protein 1

1

1

High-throughput

0.479

High

1125889

CDC73
Parafibromin

1

1

High-throughput

0.479

High

1125892

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1125893

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1125896

RD3
Protein RD3

1

2

High-throughput

0.479

High

1125909

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

1125918

UIF
UAP56-interacting factor

1

3

High-throughput

0.479

High

1125920

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

9

Small-scale

0.479

High

1125925

TOLIP
Toll-interacting protein

1

1

High-throughput

0.479

High

1125926

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1125927

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1125930

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.479

High

1125933

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

8

High-throughput

0.479

High

1125943

HDAC6
Protein deacetylase HDAC6

1

6

High-throughput

0.479

High

1125944

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

898233

R144A
E3 ubiquitin-protein ligase RNF144A

1

0

Small-scale

0.458

High

1037795

IRF8
Interferon regulatory factor 8

1

0

Small-scale

0.458

High

1125886

PHF19
PHD finger protein 19

1

0

High-throughput

0.458

High

1125895

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1125911

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

255022

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

529796

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

622053

CD53
Leukocyte surface antigen CD53

1

7

High-throughput

0.445

High

870232

S6A12
Sodium- and chloride-dependent betaine transporter

1

3

High-throughput

0.445

High

1010033

DLK1
Protein delta homolog 1

1

1

High-throughput

0.445

High

1119124

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

11

High-throughput

0.445

High

1125887

PKHA7
Pleckstrin homology domain-containing family A member 7

1

11

High-throughput

0.445

High

1125903

CD177
CD177 antigen

1

4

Small-scale

0.445

High

1125908

CTL1
Choline transporter-like protein 1

1

5

High-throughput

0.445

High

1125912

SO4A1
Solute carrier organic anion transporter family member 4A1

1

3

High-throughput

0.445

High

1125915

MF14A
Hippocampus abundant transcript 1 protein

1

2

High-throughput

0.445

High

76525

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

1

High-throughput

0.437

High

105931

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

768184

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

1125913

Q96BE0
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.437

High

896377

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.426

High

1101209

NMI
N-myc-interactor

1

0

High-throughput

0.426

High

1125882

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.426

High

1125888

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.426

High

1125899

FXL16
F-box/LRR-repeat protein 16

1

0

High-throughput

0.426

High

1125921

METH
Methionine synthase

1

0

High-throughput

0.426

High

1125890

EBLN2
Endogenous Bornavirus-like nucleoprotein 2

1

0

High-throughput

0.279

Low

1125902

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

0

High-throughput

0.279

Low

1125924

TRMO
tRNA

1

0

High-throughput

0.279

Low

1125938

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.279

Low

1125952

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

1125904

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025