Protein: GNA11
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (EC 3.6.5.-) (Guanine nucleotide-binding protein G(y) subunit alpha)

Gene: GNA11
Organism: Homo sapiens
Interactions: 102
UniProt ID: P29992

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001508 - action potential
GO:0001664 - G protein-coupled receptor binding
GO:0001750 - photoreceptor outer segment
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

640491

TA2R
Thromboxane A2 receptor

2

20

Small-scale

0.754

High

715999

RGS3
Regulator of G-protein signaling 3

2

20

Small-scale

0.754

High

715996

P2RY1
P2Y purinoceptor 1

1

20

High-throughput

0.691

High

716055

RIC8A
Chaperone Ric-8A

1

14

High-throughput

0.691

High

220438

RGS14
Regulator of G-protein signaling 14

1

20

Small-scale

0.647

High

716019

GBG3

2

20

High-throughput

0.628

High

168014

RGS13
Regulator of G-protein signaling 13

1

20

Small-scale

0.618

High

665306

EDNRB
Endothelin receptor type B

1

20

Small-scale

0.618

High

669181

EDNRA
Endothelin-1 receptor

1

15

Small-scale

0.618

High

715990

CXCR5
C-X-C chemokine receptor type 5

1

14

Small-scale

0.618

High

715997

MTR1A
Melatonin receptor type 1A

1

20

Small-scale

0.618

High

716010

CXCR4
C-X-C chemokine receptor type 4

1

19

Small-scale

0.618

High

716054

ECT2
Protein ECT2

1

14

High-throughput

0.618

High

716056

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1

3

Small-scale

0.618

High

716007

CD81
CD81 antigen

2

8

Small-scale

0.612

High

563262

CFTR
Cystic fibrosis transmembrane conductance regulator

2

4

High-throughput

0.601

High

716001

GBG10

2

20

High-throughput

0.601

High

716015

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

2

20

High-throughput

0.601

High

716061

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

2

20

High-throughput

0.601

High

240838

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

395554

ESR1
Estrogen receptor

2

10

High-throughput

0.571

High

162790

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

5

Small-scale

0.561

High

349383

TSN15
Tetraspanin-15

1

8

High-throughput

0.536

High

716000

GBG4

1

20

High-throughput

0.536

High

716003

MOT1
Monocarboxylate transporter 1

1

7

High-throughput

0.536

High

716006

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

20

High-throughput

0.536

High

716018

GBG1
Guanine nucleotide-binding protein G(T) subunit gamma-T1

1

20

High-throughput

0.536

High

716020

GBG5

1

20

High-throughput

0.536

High

716030

OTUD3
OTU domain-containing protein 3

1

3

High-throughput

0.536

High

716041

UXS1
UDP-glucuronic acid decarboxylase 1

1

1

High-throughput

0.536

High

716058

DUS22
Dual specificity protein phosphatase 22

1

15

High-throughput

0.536

High

716031

TM63B
Mechanosensitive cation channel TMEM63B

1

0

High-throughput

0.513

High

716037

CMIP
C-Maf-inducing protein

1

3

High-throughput

0.489

High

716038

ZDH23
Palmitoyltransferase ZDHHC23

1

5

High-throughput

0.489

High

716040

TEX29
Testis-expressed protein 29

1

1

High-throughput

0.489

High

716043

WDR36
WD repeat-containing protein 36

1

4

High-throughput

0.489

High

125255

LEG9
Galectin-9

1

2

High-throughput

0.479

High

247692

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

330686

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

375214

RASK
GTPase KRas

1

13

High-throughput

0.479

High

466120

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

507567

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.479

High

536570

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

578393

BRAF
Serine/threonine-protein kinase B-raf

1

14

High-throughput

0.479

High

601182

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

715989

AKT1
RAC-alpha serine/threonine-protein kinase

1

7

High-throughput

0.479

High

715993

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

715994

ZAP70
Tyrosine-protein kinase ZAP-70

1

5

Small-scale

0.479

High

715995

YAP1
Transcriptional coactivator YAP1

1

12

High-throughput

0.479

High

715998

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

3

Small-scale

0.479

High

716004

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

716005

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.479

High

716008

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

716009

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

716011

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.479

High

716012

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

716013

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.479

High

716014

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

716016

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

716017

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.479

High

716022

KIF23
Kinesin-like protein KIF23

1

14

High-throughput

0.479

High

716025

ATM
Serine-protein kinase ATM

1

3

High-throughput

0.479

High

716028

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

716029

MIDN
Midnolin

1

3

High-throughput

0.479

High

716033

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

716034

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

716045

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

716051

DUS9
Dual specificity protein phosphatase 9

1

16

High-throughput

0.479

High

716053

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

716059

HDAC6
Protein deacetylase HDAC6

1

7

High-throughput

0.479

High

716063

RNF6
E3 ubiquitin-protein ligase RNF6

1

6

High-throughput

0.479

High

716002

PAPOA
Poly(A) polymerase alpha

1

0

High-throughput

0.458

High

716027

MF13A
Transmembrane protein 180

1

0

High-throughput

0.458

High

211118

CTR4
Cationic amino acid transporter 4

1

2

High-throughput

0.445

High

484066

PGFRB
Platelet-derived growth factor receptor beta

1

6

High-throughput

0.445

High

529158

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

716021

DLK1
Protein delta homolog 1

1

1

High-throughput

0.445

High

716026

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

12

High-throughput

0.445

High

716032

PKHA7
Pleckstrin homology domain-containing family A member 7

1

14

High-throughput

0.445

High

716035

SV2B
Synaptic vesicle glycoprotein 2B

1

4

High-throughput

0.445

High

716036

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.445

High

716044

CTL1
Choline transporter-like protein 1

1

6

High-throughput

0.445

High

716047

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

14

High-throughput

0.445

High

716052

S22A4
Solute carrier family 22 member 4

1

6

High-throughput

0.445

High

716064

ITM2B
Integral membrane protein 2B

1

8

High-throughput

0.445

High

478658

HXB5
Homeobox protein Hox-B5

1

4

High-throughput

0.437

High

587988

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

590815

TIMP2
Metalloproteinase inhibitor 2

1

1

High-throughput

0.437

High

694697

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

715991

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

715992

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

716023

TFCP2
Alpha-globin transcription factor CP2

1

9

High-throughput

0.437

High

716024

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.437

High

716039

S2541
Mitochondrial carrier protein SCaMC-3L

1

3

High-throughput

0.437

High

716042

T185A
Transmembrane protein 185A

1

3

High-throughput

0.437

High

716048

UIF
UAP56-interacting factor

1

3

High-throughput

0.437

High

716049

CCNL2
Cyclin-L2

1

2

High-throughput

0.437

High

716057

ANLN
Anillin

1

9

High-throughput

0.437

High

716060

NUFP1
FMR1-interacting protein NUFIP1

1

3

High-throughput

0.437

High

716050

ZBT18
Zinc finger and BTB domain-containing protein 18

1

5

High-throughput

0.407

High

716062

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.279

Low

716046

FXL18
F-box/LRR-repeat protein 18

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025